Chronic diseases are one of the leading causes of mortality worldwide. People with chronic diseases are at high risk of experiencing psychological problems. The Indonesian government created a chronic disease management program called Prolanis (Chronic Disease Management Program). Prolanis, which is currently implemented, has not provided efforts to overcome anxiety problems in its participants. This study aimed to determine the prevalence of anxiety in the Prolanis participants. This study was a cross-sectional study involving 384 participants. The research instrument used the Zung Self-Rating Anxiety Scale questionnaire to measure the patient's anxiety level. Data collected through surveys were analysed bivariate with the chi-square test and multivariate with the ordinal logistic regression test. The study found that most elderly participants experienced mild anxiety. Based on the bivariate analysis, factors that influence the anxiety level of the participants are gender and education attainment. From multivariate analysis, education attainment was significantly associated with anxiety. Patients with chronic diseases are prone to anxiety, which impacts efforts to adopt a healthy lifestyle. Female prolanis participants and participants with low education are more likely to experience anxiety. These findings can be used as recommendations for developing mental health programs in prolanis programs.