Introduction: The 2022 nurse performance target report from various community health centers (Puskesmas) in Denpasar city indicates that both individual and organizational performance were generally satisfactory. However, performance evaluations were based solely on the nurses' core duties, without assessing the responsibilities of the programs implemented by each individual. According to data from Denpasar city, there are challenges in achieving the health Minimum Service Standards (SPM). Several factors, such as workload and work motivation, are associated with the attainment of the SPM. Therefore, this study aims to describe the relationship between workload, work motivation, and nurse performance in the community health centers of Denpasar city. Methods: This study employed a cross-sectional design conducted in the community health centers of Denpasar city during March-April 2024. The sample consisted of 121 nurses who met the inclusion criteria of having worked at a Denpasar community health center for at least one year at the time of data collection. The sampling method used was total population sampling. Data on workload, motivation, and nurse performance were collected using a questionnaire instrument via Google Forms. Data analysis was conducted using the chi-square test and multiple logistic regression analysis. Results: A total of 121 nurses participated in this study, with the majority demonstrating good performance (52.9%), high workload (50.4%), and high work motivation (59.5%). High work motivation was identified as an independent factor influencing the improvement of nurse performance in Denpasar community health centers. High work motivation tends to increase nurse performance by 4.8 times compared to low work motivation (AOR = 4.829; 95% CI = 2.205-10.575; p < 0.001). Conclusion: There is a significant relationship between nurse motivation and nurse performance in the community health centers of Denpasar city.